Biocompatible nanomaterials for targeted and controlled delivery of biomacromolecules (Record no. 75949)
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| 000 -LEADER | |
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| fixed length control field | 06112nam a2200769 a 4500 |
| 001 - CONTROL NUMBER | |
| control field | vtls000079400 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MTX |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m eo d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cn |||m|||a |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160715s2013 nyua foab 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781606506028 (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9781606506004 (print) |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaPaEBR)10707485 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)844954577 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaBNvSL)swl00402449 |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] | |
| Level of rules in bibliographic description | 201607151144 |
| Level of effort used to assign nonsubject heading access points | staff |
| -- | 201605041227 |
| -- | admin |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | CaBNVSL |
| Transcribing agency | CaBNVSL |
| Modifying agency | CaBNVSL |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QP801.P64 |
| Item number | K263 2013 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QT 36.5 |
| Item number | K263b 2013 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 574.1924 |
| Edition number | 23 |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Ebook |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kapoor, Deepak N. |
| 9 (RLIN) | 115934 |
| 245 10 - TITLE STATEMENT | |
| Title | Biocompatible nanomaterials for targeted and controlled delivery of biomacromolecules |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | Deepak N. Kapoor and Sanju Dhawan. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | New York, N.Y. : |
| Name of publisher, distributor, etc. | ASME ; |
| Place of publication, distribution, etc. | New York, N.Y. (222 East 46th Street, New York, NY 10017) : |
| Name of publisher, distributor, etc. | Momentum Press, |
| Date of publication, distribution, etc. | 2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 electronic text (47 p.) : |
| Other physical details | ill., digital file. |
| 490 1# - SERIES STATEMENT | |
| Series statement | Biomedical and nanomedical technologies |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographical references (p. 38-47) and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. Nanomaterials: a brief introduction -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2. Tissue and blood-material interactions -- 2.1 Tissue response -- 2.2 Blood response -- 2.3 Cellular response -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3. Biocompatibility -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4. Biodegradation -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 5. Biocompatible and biodegradable nanomaterials -- 5.1 Organic nanomaterials -- 5.1.1 Natural and modified natural nanomaterials -- 5.1.2 Synthetic polymeric nanomaterials -- 5.2 Stealth nanomaterials -- 5.3 Inorganic nanomaterials -- 5.3.1 Carbon nanotubes (CNTs) -- 5.3.2 Quantum dots (QDs) -- 5.3.3 End-capped mesoporous silica nanoparticles -- 5.4 Metal nanoparticles -- 5.4.1 Gold nanoparticles (Au-Nps) -- 5.4.2 Silver nanoparticles -- 5.5 Magnetic nanoparticles -- 5.6 Nanocomposites, nanofibres and nanowires -- 5.7 Hybrid nanomaterials -- 5.8 Virus-like nanocarriers -- 5.9 Multifunctional nanoparticles -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 6. Biomacromolecules -- 6.1 Cell penetrating peptides in biomacromolecular delivery -- 6.2 Targeted biomacromolecular delivery -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 7. Challenges in biomacromolecular delivery -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 8. Preparation techniques of biocompatible nanostructures -- 8.1 Top-down techniques -- 8.1.1 Dispersion of preformed polymers -- 8.1.2 Polymerization methods -- 8.1.3 Ionic gelation method for hydrophilic polymers -- 8.1.4 Hybrid assemblies -- 8.2 Bottom-up techniques -- 8.3 Scalable methods -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 9. Characterization and evaluation -- 9.1 Drug-polymer compatibility -- 9.2 Particle size and shape -- 9.3 Zeta potential -- 9.4 Drug release evaluation -- 9.5 Conformational stability -- 9.6 Biocompatibility studies -- 9.7 Pre-clinical evaluation -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 10. Regulatory perspectives -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 11. Industrial viability -- |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 12. Conclusions -- References. |
| 506 ## - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Restricted to libraries which purchase an unrestricted PDF download via an IP. |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Nanomaterials are organic or inorganic entities employed for the construction of various nanostructured devices or systems with nanometric dimensions. These nanostructures may include nanoparticles, nanowires, nanotubes, nanocapsules, nanocomposites as well as nanoporous solids. Nanomaterials have gained immense recognition, particularly in biomacromolecular delivery, owing to their capability of controlling the release rate or targeting the therapeutic moieties at molecular, cellular and organ level. Additionally, the problems of conformational and degradation stability associated with biomacromolecules like peptides, proteins, and genes have been addressed successfully by employing these nanomaterials. The degradation products of these biocompatible nanomaterials are non-toxic, non-immunogenic and easily resorbable by the regular physiological processes. The present chapter endeavors to describe the role of nanomaterials in the design, fabrication and development of various nanostructured, biomacromolecular delivery systems and devices. The chapter presents a discussion on various physicochemical properties, preparation techniques and analytical tools for characterizing these systems. The mechanisms of cellular internalization of nanomaterial based targeted systems are also discussed. Taking lead from various successful case studies, the present chapter provides a bird's eye view on the current advances in the field of nanomaterial based biomacromolecular delivery. A brief overview pertaining to the regulatory requirements and commercialization of these systems is also included. Various challenges posed during the development, scale up and large-scale production is also discussed. In a nutshell, besides, providing the salient details about the formulation and applications of biocompatible nanomaterials, the chapter would act as a ready reference for drug delivery scientists, device fabrication engineers and medical researchers working in this area. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Also available in print. |
| 538 ## - SYSTEM DETAILS NOTE | |
| System details note | Mode of access: World Wide Web. |
| 538 ## - SYSTEM DETAILS NOTE | |
| System details note | System requirements: Adobe Acrobat reader. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Title from PDF t.p. (viewed on May 29, 2013). |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Macromolecules. |
| 9 (RLIN) | 115935 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nanostructured materials. |
| 9 (RLIN) | 115936 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug delivery systems. |
| 9 (RLIN) | 115937 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nanomedicine. |
| 9 (RLIN) | 115923 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nanostructures. |
| 9 (RLIN) | 115938 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Delivery Systems. |
| 9 (RLIN) | 115939 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nanomedicine. |
| 9 (RLIN) | 115923 |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | nanomaterials |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | engineering |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | organic |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | inorganic entities |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | biomacromolecular delivery |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | regulatory requirements |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | commercialization |
| 653 ## - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | biocompatible |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dhawan, Sanju. |
| 9 (RLIN) | 115940 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| International Standard Book Number | 9781606506004 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Biomedical & nanomedical technologies. |
| 9 (RLIN) | 115941 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://portal.igpublish.com/iglibrary/search/MPB0000077.html">http://portal.igpublish.com/iglibrary/search/MPB0000077.html</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | eBook |
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